Endocrine Abstracts

Diabetic ketoacidosis (DKA) seen in 10–70% of patients with type 1 diabetes mellitus (DM1) has a significant risk of mortality. We present a DKA in a patient with DM1 resulted in hypokalemia related ECG abnormalities that the diagnosis needed to be differentiated from acute coronary syndrome. A 18-year-old women without any significant past medical history admitted to hospital with a two day history of fatique, weakness, nausea, vomiting. Patient appeared hipovolemic. Vit...

Objective: Our aim was to evaluate C-reactive protein (CRP) and serum vaspin levels in women with polycystic ovary syndrome (PCOS) or polycystic ovaries (PCO).Design: Twenty-four women with PCOS and 23 women with PCO constituted the study groups. The control group comprised 24 healthy women.Methods: Homeostatic model assessment for insulin resistance (HOMA-IR), CRP and serum vaspin levels were measured. The receiver operating chara...

Thyroid hormones play an important role in bone metabolism. The potential action of prolonged levothyroxine therapy on bone mass reduction is stil a matter of debate.The aim of our one year prospective study was to elucidate whether longterm suppressive thyroid hormone therapy in patient with differentiated thyroid cancer (DTC) affects bone metabolism, osteoprotegerin (OPG) and soluble receptor activator of nuclear factor kβ ligand (sRANK-L) and is ...

Background: Clinical practice guidelines on diabetes mellitus (DM) have been developed in 2006 by The Society of Endocrinology and Metabolism of Turkish (SEMT). The ongoing ADMIRE Project is designed to evaluate the effect of implementation of various activities to increase the awareness of physicians on the adherence to SEMT guidelines. The first phase results of the project is presented.Methods: Of 180 physicians evaluated previous 12 months’ medi...

Introduction: Hypothyroidism is a well-known cause of secondary dyslipidemia, and its link to atherosclerosis has been known for long time. The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) offer important benefits for the large population of individuals at high risk for coronary heart disease. It was aimed to invastigation the relations of the secondary hyperlipidemia included overt and subclinical hypothyroidism and increased serum creatine k...

Introduction: Patients with extremely high triglyceride levels and associated lipemia are at high risk for acute pancreatitis. Hypertryiglycerideamia can be can be provoked when triglyceride levels exceed 1.000 mg/dl of acute pancreatitis.Materials and method: In 7 patients with hyperlipidemic pancreatitis was evaluated. In addition to the standard therapy, they were treated with triglyceride apheresis. Acute pancreatitis was diagnosed based on the prese...

Introduction: Hemochromatosis is an iron storage disease characterized by iron deposition in parenchymal cells due to increased intestinal iron absorption. Iron overload leads to tissue damage and dysfunction particularly in the liver, pancreas, heart, joints, and pituitary gland. Panhypopituitarism is a clinical condition in which the anterior pituitary gland hormones are deficient. Herein we report a very rare case of panhypopituitarism due to hemochromatosis.<p class="a...

Background and aim: Thyroid gland is considered to be rare site of extrapulmonary tuberculosis (tbc), even in countries with a high prevalance. The aim of this study is to ases the correlation between thyroid nodules and pulmonary tbc with fine needle aspiration cytology (FNAC) and to find out the incidence of thyroid gland tbc.Material and methods: The main purpose of this study is to find out tbc incidence in pulmonary tbc patients with thyroid nodules...

Aim: To investigate the relationship between serum growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels, seminal plasma GH and IGF-1 levels, and sperm parameters in acromegalic patients.Methods: A cross-sectional study was conducted on 24 acromegaly patients (acromegaly group), 11 non-functioning adenoma (NFA) patients (NFA group), and 16 healthy men (control group). Seminal plasma GH and IGF-1 levels were measured. Semen parameters and se...

Aim: To determine the prevalence of impulse control disorder (ICD) in patients with Cushing’s disease (CD) treated with cabergoline (CBG) compared to CBG-naive patients with CD.Methods: We performed a cross-sectional study in patients with CD followed at 5 referral centers based in Istanbul. Eligible patients with CD were those with current CBG treatment for ≥ 3 months. Eligible controls were CBG-naive patients with CD that were matched for ag...